Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606980 | 0.83 | CA12 (0.51) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5606977 | 0.83 | CA12 (0.51) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL21758695 | 0.82 | APP (0.50) | MEN1KMT2AALDH1A1PSMD14APP | |
| SCHEMBL11242541 | 0.82 | GSK3B (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6388241 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8408159 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6233430 | 0.80 | KMT2A (0.68) | MEN1KMT2AALDH1A1PSMD14APP | |
| SCHEMBL8377557 | 0.79 | KMT2A (0.53) | MEN1KMT2AALDH1A1PSMD14APP | |
| SCHEMBL8377554 | 0.79 | KMT2A (0.53) | MEN1KMT2AALDH1A1PSMD14APP | |
| SCHEMBL13172008 | 0.78 | APP (0.63) | MEN1KMT2AALDH1A1APPHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305024-A | A kind of synthetic method of Beloranib intermediate | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | disclosed |