SCHEMBL6233430

SCHEMBL6233430

CCOC(=O)C(=Cc1ccc(N(C)C)cc1)C(=O)OCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.68
MEN1 O00255 8/20 0.68
MAPT P10636 8/20 0.67
LMNA P02545 4/20 0.67
NPSR1 Q6W5P4 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67
S1PR4 O95977 1/20 0.67
S1PR1 P21453 1/20 0.67
MAPK1 P28482 1/20 0.67
NR1H4 Q96RI1 1/20 0.55
ALDH1A1 P00352 5/20 0.53
PSMD14 O00487 1/20 0.53
KDM4E B2RXH2 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HSP90AA1 P07900 2/20 0.52
MITF O75030 1/20 0.52
HTT P42858 1/20 0.52
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28367377 0.92 KMT2A (0.62) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL11434906 0.92 KMT2A (0.58) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL21183312 0.90 MEN1 (0.72) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL1068265 0.88 MEN1 (0.85) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL7945104 0.86 MEN1 (0.66) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL19049494 0.86 MEN1 (0.66) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL8377554 0.86 KMT2A (0.53) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL11484470 0.86 MEN1 (0.66) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL8377557 0.86 KMT2A (0.53) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL10887368 0.83 KMT2A (0.47) KMT2AMEN1MAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914322-B Polymerizable composition for optical material, and use thereof 三井化学株式会社 2022-08-23 CN disclosed
CN-110914322-A Polymerizable composition for optical material, and use thereof 三井化学株式会社 2020-03-24 CN disclosed
EP-1553449-B1 ACTIVE ENERGY RAY SENSITIVE RESIN COMPOSITION, ACTIVE ENERGY RAY SENSITIVE RESIN FILM AND METHOD FOR FORMING PATTERN USING SAID FILM MURAKAMI CO LTD (JP) 2016-01-20 EP disclosed
US-20050227166-A1 Active energy ray sensitive resin composition, active energy ray sensitive resin film and method for forming pattern using said film MURAKAMI CO., LTD. (JP) 2005-10-13 US disclosed
EP-1553449-A1 ACTIVE ENERGY RAY SENSITIVE RESIN COMPOSITION, ACTIVE ENERGY RAY SENSITIVE RESIN FILM AND METHOD FOR FORMING PATTERN USING SAID FILM Murakami Co., Ltd. (JP) 2005-07-13 EP disclosed
US-4613499-A Substituted cinnamal dialkyl malonates in sunscreening, skin care compositions VAN DYK & COMPANY INC. (US) 1986-09-23 US disclosed
US-4592906-A Ester of p-dimethylaminocinnamic acid GRAESSER LABORATORIES, LTD. (GB) 1986-06-03 US disclosed
EP-0171875-A1 Liquid cinnamal dialkyl malonates as sole organic sunscreens VAN DYK & COMPANY, INC. (US) 1986-02-19 EP disclosed
EP-0153089-A1 Ultra-violet absorbing compounds and compositions containing said compounds GRAESSER LABORATORIES LIMITED (GB) 1985-08-28 EP disclosed
US-4515774-A NON-POLAR OIL CARRIER VAN DYK & COMPANY INC. (US) 1985-05-07 US disclosed
US-4457911-A Dialkyl malonates as organic sunscreen adjuvants VAN DYK & COMPANY INC. (US) 1984-07-03 US disclosed
EP-0100651-A1 Dialkyl malonates as organic suncreen adjuvants VAN DYK & COMPANY, INC. (US) 1984-02-15 EP disclosed
US-4200464-A ALKYL-3,4-METHYLENEDIOXY-A-CYANOCINNAMATES FUJI PHOTO FILM CO., LTD. (JP) 1980-04-29 US disclosed
US-4104368-A STEARYLDIMETHYLBENZYLAMMONIUM P-AMINOBENZOATE MILLMASTER ONYX CORPORATION (US) 1978-08-01 US disclosed