SCHEMBL28322709

SCHEMBL28322709

OC1c2ccccc2C=CC1c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.36
KDR P35968 1/20 0.36
PRCP P42785 1/20 0.35
CYP2D6 P10635 1/20 0.34
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HTR6 P50406 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28322712 1.00 RET (0.36) RETKDRPRCPCYP2D6RAB9A
SCHEMBL28323756 0.85 CYP2D6 (0.38) CYP2D6KMT2AHTR6
SCHEMBL28323755 0.85 CYP2D6 (0.38) CYP2D6KMT2AHTR6
SCHEMBL28876953 0.84 PRCP (0.36) RETPRCPCYP2D6KMT2AALDH1A1
SCHEMBL28876954 0.84 PRCP (0.36) RETPRCPCYP2D6KMT2AALDH1A1
SCHEMBL28323765 0.84 MAPT (0.38) GAAKMT2AALDH1A1SLC6A3
SCHEMBL28323766 0.84 MAPT (0.38) GAAKMT2AALDH1A1SLC6A3
SCHEMBL28323744 0.83 GAA (0.35) PRCPCYP2D6GAAHTR6
SCHEMBL28322722 0.83 HDAC4 (0.36) CYP2D6GAAKMT2AHTR6
SCHEMBL28322723 0.83 HDAC4 (0.36) CYP2D6GAAKMT2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107235843-B A kind of synthetic method of 2- phenyl -1,2- dihydronaphthalene -1- alcohol racemic compound and its derivative 华南师范大学 2019-08-13 CN disclosed