SCHEMBL28323756

SCHEMBL28323756

OC1c2ccccc2C=C[C@@H]1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
EDNRA P25101 1/20 0.34
SIGMAR1 Q99720 6/20 0.33
PARP3 Q9Y6F1 1/20 0.33
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28323755 1.00 CYP2D6 (0.38) CYP2D6HTR2AHTR6EDNRASIGMAR1
SCHEMBL28876953 0.87 PRCP (0.36) CYP2D6HTR2AHTR6SIGMAR1MEN1
SCHEMBL28876954 0.87 PRCP (0.36) CYP2D6HTR2AHTR6SIGMAR1MEN1
SCHEMBL28322709 0.85 RET (0.36) CYP2D6HTR6KMT2A
SCHEMBL28322723 0.85 HDAC4 (0.36) CYP2D6HTR2AHTR6MEN1KMT2A
SCHEMBL28323743 0.85 GAA (0.35) CYP2D6HTR2AHTR6ATM
SCHEMBL28322722 0.85 HDAC4 (0.36) CYP2D6HTR2AHTR6MEN1KMT2A
SCHEMBL28322712 0.85 RET (0.36) CYP2D6HTR6KMT2A
SCHEMBL28323744 0.85 GAA (0.35) CYP2D6HTR2AHTR6ATM
SCHEMBL8959368 0.85 MAOB (0.35) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107235843-B A kind of synthetic method of 2- phenyl -1,2- dihydronaphthalene -1- alcohol racemic compound and its derivative 华南师范大学 2019-08-13 CN disclosed