Formic Acid Methyl Ester

Formic Acid Methyl Ester

SCHEMBL28323293

COC=O.O=[N+]([O-])c1cccnc1Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
PDE10A Q9Y233 1/20 0.45
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 1/20 0.42
PAX8 Q06710 1/20 0.41
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 3/20 0.41
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TXNRD1 Q16881 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482300 0.87 PDE10A (0.56) ALDH1A1PDE10AMEN1KMT2APOLB
SCHEMBL75026 0.87 PDE10A (0.56) ALDH1A1PDE10AMEN1KMT2APOLB
Ethoxycarbonyl Group SCHEMBL28857317 0.85 ALDH1A1 (0.43) ALDH1A1PDE10AMEN1KMT2APOLB
Formic Acid SCHEMBL28205171 0.85 PDE10A (0.49) ALDH1A1PDE10AMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL28324118 0.85 PDE10A (0.55) ALDH1A1PDE10AMEN1KMT2APOLB
SCHEMBL28114821 0.85 PDE10A (0.55) ALDH1A1PDE10AMEN1KMT2APOLB
Formaldehyde SCHEMBL28205148 0.83 PDE10A (0.53) ALDH1A1PDE10AMEN1KMT2APOLB
Cyanide SCHEMBL28864179 0.82 PDE10A (0.51) ALDH1A1PDE10AMEN1KMT2APOLB
Formic Acid Methyl Ester SCHEMBL29210524 0.81 ALDH1A1 (0.48) ALDH1A1PDE10AMEN1KMT2APOLB
Acetic Acid SCHEMBL4769636 0.81 ALDH1A1 (0.49) ALDH1A1PDE10AMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325530-A GLP-1 receptor agonists and uses thereof 辉瑞大药厂 2019-10-11 CN disclosed