Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8164708 | 0.97 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8349273 | 0.97 | — | — | |
| Acetic Acid SCHEMBL9488874 | 0.93 | FFAR3 (0.47) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8169115 | 0.93 | FFAR3 (0.47) | FFAR3LCKFYNCA1CA4 | |
| Acetone SCHEMBL131531 | 0.86 | — | — | |
| Acetic Acid SCHEMBL8164706 | 0.86 | FFAR3 (0.54) | FFAR3LCKFYNCA1CA4 | |
| Acetone SCHEMBL10925741 | 0.86 | CA1 (0.47) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8349268 | 0.86 | FFAR3 (0.54) | FFAR3LCKFYNCA1CA4 | |
| Acetone SCHEMBL28417432 | 0.86 | CA1 (0.47) | FFAR3LCKFYNCA1CA4 | |
| Acetone SCHEMBL28917606 | 0.86 | CA1 (0.47) | FFAR3LCKFYNCA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110269176-A | Enhance the method for calcium dissolution in bighead processing | 重庆两江生态渔业发展有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-110269176-A | Enhance the method for calcium dissolution in bighead processing | 重庆两江生态渔业发展有限公司 | 2019-09-24 | — | — | CN | disclosed |