Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087256 | 0.81 | LMNA (0.47) | LMNAALDH1A1MEN1BLMHBB | |
| SCHEMBL14984809 | 0.73 | LMNA (0.50) | LMNAALDH1A1HTTMAPTTSHR | |
| SCHEMBL28093161 | 0.71 | LMNA (0.48) | LMNAALDH1A1HTTMAPTTSHR | |
| SCHEMBL28511337 | 0.69 | LMNA (0.41) | LMNAALDH1A1MAPTTSHR | |
| SCHEMBL19859133 | 0.68 | LMNA (0.46) | LMNAALDH1A1HTTMAPTTSHR | |
| SCHEMBL12505330 | 0.68 | LMNA (0.65) | LMNAALDH1A1MEN1BLMKMT2A | |
| SCHEMBL72471 | 0.67 | LMNA (0.62) | LMNAALDH1A1HTTMAPTTSHR | |
| SCHEMBL18885501 | 0.66 | LMNA (0.40) | LMNAMAPTTSHR | |
| SCHEMBL31402602 | 0.65 | LMNA (0.60) | LMNAALDH1A1BLMHTTMAPT | |
| SCHEMBL9362276 | 0.65 | LMNA (0.46) | LMNAALDH1A1HTTMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267948-A | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and methods of making the modulators | 弗特克斯药品有限公司 | 2019-09-20 | — | — | CN | disclosed |