Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 2/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199995 | 0.86 | IDH1 (0.49) | PSMB8DAOIDH1F11AHR | |
| SCHEMBL9256747 | 0.77 | DAO (0.58) | PSMB8DAOIDH1F11ALDH1A1 | |
| SCHEMBL31568898 | 0.76 | AHR (0.44) | AHRNOS1DYRK1AALDH1A1NR4A2 | |
| SCHEMBL6336055 | 0.76 | AHR (0.44) | AHRNOS1DYRK1AALDH1A1NR4A2 | |
| SCHEMBL806286 | 0.76 | DAO (0.49) | DAOIDH1ALDH1A1HSD17B10GRIN2D | |
| SCHEMBL393268 | 0.76 | MEN1 (0.41) | ALOX15ALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL29820804 | 0.76 | DAO (0.49) | DAOAHRDYRK1A | |
| SCHEMBL18292209 | 0.76 | CDK5 (0.48) | IDH1ALOX15 | |
| SCHEMBL29763767 | 0.75 | AOC3 (0.48) | DAODYRK1AALDH1A1HPGDHSD17B10 | |
| SCHEMBL723282 | 0.75 | AOC3 (0.48) | DAODYRK1AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440496-B | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108689907-A | A method of preparing 2- nitroindole derivatives | 苏州大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-108440496-A | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2018-08-24 | — | — | CN | disclosed |