Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28324291 | 0.91 | DPP7 (0.39) | OPRK1 | |
| SCHEMBL19064197 | 0.86 | OPRK1 (0.30) | OPRK1ALDH1A1 | |
| SCHEMBL15718081 | 0.80 | GBA1 (0.32) | — | |
| SCHEMBL15720653 | 0.78 | GAA (0.33) | ALDH1A1 | |
| SCHEMBL534292 | 0.77 | GBA1 (0.30) | — | |
| SCHEMBL20702387 | 0.77 | TACR3 (0.37) | OPRK1OPRD1HSD17B10MAPTALDH1A1 | |
| SCHEMBL20702384 | 0.77 | TACR3 (0.37) | OPRK1OPRD1HSD17B10MAPTALDH1A1 | |
| SCHEMBL4328443 | 0.77 | TACR3 (0.37) | OPRK1OPRD1HSD17B10MAPTALDH1A1 | |
| SCHEMBL28324290 | 0.75 | DPP8 (0.30) | — | |
| SCHEMBL3605608 | 0.75 | MEN1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751156-A | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using the same | 梅比斯发现公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110392571-A | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using the same | 梅比斯发现公司 | 2019-10-29 | — | — | CN | disclosed |