Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | RAB9A | P51151 | 2/20 | 0.80 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.76 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497242 | 0.89 | KMT2A (1.00) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL18497237 | 0.86 | KMT2A (0.78) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL18497234 | 0.86 | PAX8 (1.00) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL27846900 | 0.85 | KMT2A (0.76) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| Hydrochloric Acid SCHEMBL18497226 | 0.85 | PAX8 (0.97) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL28217707 | 0.82 | KMT2A (0.72) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL20476787 | 0.82 | KMT2A (0.71) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL4014550 | 0.79 | MEN1 (0.67) | KMT2AMEN1RAB9APAX8ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL18497239 | 0.79 | KMT2A (0.80) | KMT2AMEN1RAB9APAX8TXNRD1 | |
| SCHEMBL4014551 | 0.79 | MEN1 (0.67) | KMT2AMEN1RAB9APAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382486-A | Heteroaryl sulfonyl substituted pyridines and their use in the treatment of cancer | 欧比力克治疗公司 | 2019-10-25 | — | — | CN | disclosed |