Fluoride

Fluoride

SCHEMBL28325331

C=C=Cc1ccccc1.F.S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 1/20 0.43
MAOB P27338 2/20 0.38
CYP2A6 P11509 1/20 0.38
LMNA P02545 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
NFE2L2 Q16236 1/20 0.32
CYP19A1 P11511 1/20 0.32
MAOA P21397 1/20 0.32
TRPA1 O75762 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 2/20 0.31
HDAC3 O15379 1/20 0.31
TNKS O95271 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370016 0.95
SCHEMBL27895709 0.92 ALDH1A1 (0.46) ALDH1A1TSHRMAOBCYP2A6LMNA
Water SCHEMBL28150278 0.92 ALDH1A1 (0.46) ALDH1A1TSHRMAOBCYP2A6LMNA
SCHEMBL28325527 0.85 ALDH1A1 (0.40) ALDH1A1TSHRMAOBCYP2A6LMNA
SCHEMBL27977239 0.85 ALDH1A1 (0.40) ALDH1A1TSHRMAOBCYP2A6LMNA
SCHEMBL28959768 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMAOBCYP2A6LMNA
Styrene SCHEMBL28863663 0.81 ALDH1A1 (0.61) ALDH1A1TSHRMAOBCYP2A6LMNA
Nitrous Acid SCHEMBL27847130 0.81 ALDH1A1 (0.37) ALDH1A1TSHRCYP2A6LMNAL3MBTL1
SCHEMBL28015427 0.80 ALDH1A1 (0.43) ALDH1A1TSHRLMNAL3MBTL1MAPK1
Acetic Acid SCHEMBL27594704 0.77 AKR1C3 (0.42) ALDH1A1TSHRLMNAMAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256623-A Perfluoroalkyl tetrafluoro sulphur methylene styrol copolymer and its application 苏州大学 2019-09-20 CN disclosed