Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 6/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166122 | 0.93 | ACMSD (0.58) | ACMSDNOTUMKMODHODHIKBKE | |
| SCHEMBL31414507 | 0.80 | KDM4E (0.41) | ACMSDSMN1; SMN2MAPTPOLB | |
| SCHEMBL28822507 | 0.79 | ACMSD (0.64) | ACMSDNOTUMKMODHODHSMN1; SMN2 | |
| SCHEMBL13544473 | 0.78 | TSHR (0.55) | ACMSDNOTUMKMODHODHACLY | |
| SCHEMBL1725857 | 0.78 | ACMSD (0.53) | ACMSDNOTUMKMODHODHIKBKE | |
| SCHEMBL10148375 | 0.78 | ACMSD (0.53) | ACMSDNOTUMKMODHODHACLY | |
| SCHEMBL27881571 | 0.76 | ACMSD (0.86) | ACMSDDHODHWDR5LCK | |
| SCHEMBL29156207 | 0.76 | ACMSD (0.69) | ACMSDNOTUMKMODHODHIKBKE | |
| SCHEMBL18284052 | 0.75 | ACMSD (0.50) | ACMSDNOTUMKMODHODHTBK1 | |
| SCHEMBL23374556 | 0.74 | ACMSD (0.75) | ACMSDKMODHODHIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006827-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | GENZYME CORPORATION (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-106061963-B | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2019-10-22 | — | — | CN | disclosed |