SCHEMBL28326239

SCHEMBL28326239

NN1CCN(S(=O)(=O)O)CC1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 2/20 0.31
KMT2A Q03164 1/20 0.31
NT5E P21589 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746338 0.85
SCHEMBL25726143 0.74 POLB (0.33) POLBTSHRKMT2A
SCHEMBL1650338 0.73
SCHEMBL1335069 0.73
SCHEMBL3232994 0.72 LMNA (0.42) TSHRKMT2A
SCHEMBL2778744 0.72 POLB (0.43) POLBTSHRKMT2A
SCHEMBL3681074 0.71 CA1 (0.55) CA1CA2POLBTSHRKMT2A
SCHEMBL15247350 0.71 CA1 (0.55) CA1CA2POLBTSHRKMT2A
SCHEMBL2590451 0.71 CA1 (0.48) CA1CA2POLBTSHRKMT2A
SCHEMBL15247354 0.71 CA1 (0.55) CA1CA2POLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110267944-A Compounds useful for treating gastrointestinal disorders 阿德利克斯股份有限公司 2019-09-20 CN claimed