Naphthalene

Naphthalene

SCHEMBL28326317

C=C.C=COC(C)=O.c1ccc2ccccc2c1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 3/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX12 P18054 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
EGFR P00533 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
ALOX15 P16050 1/20 0.40
JAK1 P23458 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
PLAU P00749 1/20 0.39
AKT1 P31749 1/20 0.34
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL27569184 0.98 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDCYP3A4ALOX12
Phenol SCHEMBL9115796 0.84 TDP1 (0.42) ALDH1A1KDM4EHPGDCYP3A4HSD17B10
O-Xylene SCHEMBL7063031 0.83 TSHR (0.42) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10
SCHEMBL28294859 0.83 KDM4E (0.42) ALDH1A1KDM4EHPGDCYP3A4ALOX12
Styrene SCHEMBL21448340 0.82 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1MEN1MAPT
Styrene SCHEMBL10608565 0.82 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1MEN1MAPT
Phthalic Acid SCHEMBL27946592 0.82 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10
Benzene SCHEMBL27367860 0.82 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHSD17B10TDP1
Ethylene SCHEMBL10561806 0.82 ALDH1A1 (0.42) ALDH1A1HSD17B10TDP1TP53TSHR
Ethylene SCHEMBL994924 0.82 ALDH1A1 (0.42) ALDH1A1HSD17B10TDP1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110350151-A Protective coating and its manufacturing method containing lithium electrode 通用汽车环球科技运作有限责任公司 2019-10-18 CN disclosed