Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054679 | 0.86 | POLB (0.58) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29170681 | 0.86 | EPHX2 (0.52) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL28469887 | 0.83 | CA1 (0.52) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8227151 | 0.81 | CA1 (0.50) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28468138 | 0.80 | CA1 (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9938209 | 0.80 | CNR1 (0.60) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28326337 | 0.79 | MAPT (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13232496 | 0.79 | MAPT (0.61) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3036382 | 0.79 | MAPT (0.54) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19808773 | 0.78 | CNR1 (0.49) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437086-A | A kind of method of TEMPO and TBN catalysis N- alkylated reaction | UNIV WEIFANG MEDICAL | 2019-11-12 | — | — | CN | disclosed |
| CN-109336777-A | A kind of method that catalysis of iodine generates Beta-aminoketones compound | 潍坊医学院 | 2019-02-15 | — | — | CN | disclosed |