Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327763 | 0.84 | TP53 (0.42) | L3MBTL1GAATRPA1 | |
| SCHEMBL23221250 | 0.84 | ALDH1A1 (0.45) | L3MBTL1AKT1GAATRPA1PPARG | |
| SCHEMBL28326466 | 0.83 | MAP2K4 (0.46) | FYNMAP2K4BRAFTRPA1 | |
| SCHEMBL28326483 | 0.83 | FYN (0.40) | FYNMAP2K4BRAFAKT1PDCD1 | |
| SCHEMBL28326468 | 0.83 | FYN (0.40) | FYNMAP2K4BRAFL3MBTL1TRPA1 | |
| SCHEMBL28326480 | 0.83 | FYN (0.54) | FYNGAACHEK1PPARG | |
| SCHEMBL28327747 | 0.82 | DPP4 (0.42) | FYNMAP2K4BRAFAKT1CHEK1 | |
| SCHEMBL28326471 | 0.81 | BRAF (0.51) | FYNMAP2K4BRAFGAACHEK1 | |
| SCHEMBL28327759 | 0.78 | GAA (0.46) | GAATRPA1PPARG | |
| SCHEMBL8188945 | 0.77 | HDAC8 (0.50) | MGLLHDAC8HDAC6PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110423239-A | 1,3- oxazines and 1,2,3- triazole derivative and its synthetic method and application | UNIV KUNMING SCIENCE & TECHNOLOGY | 2019-11-08 | — | — | CN | disclosed |