Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566699 | 0.94 | PRMT5 (0.48) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL565890 | 0.88 | CARM1 (0.46) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL566650 | 0.82 | CARM1 (0.58) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL3507700 | 0.72 | ITGB3 (0.57) | CARM1ITGB3ITGA2BCD274S1PR1 | |
| SCHEMBL2182632 | 0.71 | S1PR1 (0.55) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL4423589 | 0.71 | ITGB3 (0.51) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL564883 | 0.70 | CD274 (0.45) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL2179759 | 0.69 | S1PR1 (0.53) | PRMT5WDR77CARM1ITGB3ITGA2B | |
| SCHEMBL3502972 | 0.68 | MAOB (0.54) | ITGB3ITGA2BHRH3CYP2D6HRH1 | |
| SCHEMBL13980737 | 0.68 | S1PR1 (0.53) | PRMT5WDR77ITGB3ITGA2BCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | claimed |