Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530670 | 0.89 | EPHX2 (0.46) | KMT2AEPHX2EPHX1FABP7FABP5 | |
| SCHEMBL7920181 | 0.88 | KMT2A (0.52) | KMT2AEPHX2FOLH1MDM4TP53 | |
| SCHEMBL1855344 | 0.86 | EPHX2 (0.53) | KMT2AEPHX2EPHX1 | |
| SCHEMBL20530627 | 0.85 | EPHX2 (0.47) | KMT2AEPHX2MDM4TP53EPHX1 | |
| SCHEMBL29618948 | 0.84 | KMT2A (0.53) | KMT2AEPHX2FABP7FABP5 | |
| SCHEMBL119110 | 0.84 | KMT2A (0.53) | KMT2AEPHX2FABP7FABP5 | |
| SCHEMBL29679265 | 0.84 | KMT2A (0.53) | KMT2AEPHX2FABP7FABP5 | |
| SCHEMBL20530636 | 0.84 | EPHX2 (0.47) | KMT2AEPHX2MDM4TP53EPHX1 | |
| SCHEMBL30466803 | 0.84 | EPHX2 (0.47) | KMT2AEPHX2MDM4TP53EPHX1 | |
| SCHEMBL30421786 | 0.83 | KMT2A (0.56) | KMT2AEPHX2MDM4TP53FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494442-A | The big ring of peptide and its purposes in treatment bacterium infection | HOFFMANN LA ROCHE | 2019-11-22 | — | — | CN | disclosed |