Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | FABP7 | O15540 | 3/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28330792 | 0.88 | KMT2A (0.49) | KMT2AEPHX2FABP7FABP5FABP3 | |
| SCHEMBL1855193 | 0.87 | EPHX2 (0.53) | KMT2AEPHX2 | |
| SCHEMBL29678978 | 0.85 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL118108 | 0.85 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL29402075 | 0.85 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL2744370 | 0.85 | KMT2A (0.48) | KMT2AEPHX2FABP7FABP5FABP3 | |
| Benzoic Acid SCHEMBL27028192 | 0.83 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL30421786 | 0.83 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5MDM4 | |
| SCHEMBL119384 | 0.83 | KMT2A (0.56) | KMT2AEPHX2FABP7FABP5MDM4 | |
| SCHEMBL6421736 | 0.82 | KMT2A (0.49) | KMT2AEPHX2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228985-B1 | COMPOUNDS THAT INHIBIT INTERACTION OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR WITH UROKINASE-TYPE PLASMINOGEN RECEPTOR; ANTITUMOR AGENTS; ANTIMETASTASIS AGENTS; ANTIARTHRITIC AGENTS FOR RHEUMATOID ARTHRITIS | SCHERING CORPORATION | 2001-05-08 | — | — | US | disclosed |