Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL4255966 | 0.97 | TP53 (0.57) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL7907061 | 0.93 | TP53 (0.53) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL2064180 | 0.90 | TP53 (0.57) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL28166068 | 0.90 | TP53 (0.57) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL2064182 | 0.90 | TP53 (0.57) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL27870655 | 0.87 | TP53 (0.53) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL11342883 | 0.84 | TP53 (0.50) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL11342295 | 0.84 | TP53 (0.50) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL11342886 | 0.84 | TP53 (0.50) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL28104528 | 0.84 | CA2 (0.50) | TP53LMNAHPGDHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382635-A | Electrodepositable coating composition | PPG工业俄亥俄公司 | 2019-10-25 | — | — | CN | disclosed |