Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834546 | 0.89 | CA1 (0.61) | KMT2AALDH1A1MAPTMAPK1NPSR1 | |
| Ammonia Solution, Strong SCHEMBL7995827 | 0.86 | CA1 (0.58) | KMT2AALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL8298 | 0.83 | — | — | |
| SCHEMBL7024215 | 0.83 | — | — | |
| SCHEMBL7893366 | 0.83 | ESR1 (0.52) | ALDH1A1HTTCA1CA2CA7 | |
| SCHEMBL15232928 | 0.82 | CA1 (0.52) | KMT2AALDH1A1MAPK1CA12CA1 | |
| Ammonia Solution, Strong SCHEMBL7995946 | 0.81 | ESR1 (0.50) | ALDH1A1HTTCA1CA2CA7 | |
| SCHEMBL9771604 | 0.81 | NFE2L2 (0.53) | NFE2L2KMT2ALMNAALDH1A1HTT | |
| SCHEMBL3752413 | 0.81 | NFE2L2 (0.53) | NFE2L2KMT2ALMNAALDH1A1HTT | |
| SCHEMBL13427765 | 0.81 | NFE2L2 (0.53) | NFE2L2KMT2ALMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437230-A | A kind of three-level aminated compounds and biphosphine ligand, wherein mesosome and preparation method | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-11-12 | — | — | CN | disclosed |