⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827340 | 0.95 | TSHR (0.32) | — | |
| SCHEMBL2831752 | 0.92 | TSHR (0.36) | — | |
| SCHEMBL1840485 | 0.92 | TSHR (0.36) | — | |
| SCHEMBL2832088 | 0.92 | TSHR (0.36) | — | |
| SCHEMBL873141 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL11029381 | 0.86 | — | — | |
| SCHEMBL19392125 | 0.79 | — | — | |
| SCHEMBL3164465 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL14059088 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL4624265 | 0.78 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250191-B1 | TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING | NOVO NORDISK AS (DK) | 2024-01-17 | — | — | EP | claimed |
| EP-2637698-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2022-04-20 | — | — | EP | claimed |
| EP-2932981-B1 | Albumin-binding derivatives of GLP-1 | NOVO NORDISK AS (DK) | 2021-06-16 | — | — | EP | claimed |
| EP-3225631-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2019-01-09 | — | — | EP | claimed |
| EP-2190872-B1 | GLUCAGON-LIKE PEPTIDE-1 DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVO NORDISK AS (DK) | 2018-03-14 | — | — | EP | claimed |
| EP-3010546-B1 | GLP-1 DERIVATIVES AND USES THEREOF | NOVO NORDISK AS (DK) | 2017-08-09 | — | — | EP | claimed |
| EP-2846824-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2017-04-05 | — | — | EP | claimed |
| EP-2753642-B1 | GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2017-03-01 | — | — | EP | claimed |
| EP-2696687-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2016-10-26 | — | — | EP | claimed |
| EP-2190873-B1 | TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK AS (DK) | 2015-07-22 | — | — | EP | claimed |
| EP-2398483-B1 | OXYNTOMODULIN ANALOGS | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | claimed |
| EP-1863521-B1 | EXTENDED GLP-1 COMPOUNDS | NOVO NORDISK AS (DK) | 2014-05-07 | — | — | EP | claimed |
| EP-2045265-B1 | GLP-1 (Glucagon-like peptide-1) fusion polypeptides with increased peptidase resistance | BIOCOMPATIBLES UK LTD (GB) | 2012-11-21 | — | — | EP | claimed |
| EP-1926748-B1 | GLP-1 ( GLUCAGON-LIKE PEPTIDE-1 ) FUSION POLYPEPTIDES WITH INCREASED PEPTIDASE RESISTANCE | BIOCOMPATIBLES UK LTD (GB) | 2012-08-29 | — | — | EP | claimed |
| EP-1863839-B1 | ACYLATED GLP-1 COMPOUNDS | NOVO NORDISK AS (DK) | 2010-08-04 | — | — | EP | claimed |
| EP-1704165-B1 | GLP-1 COMPOUNDS | NOVO NORDISK AS (DK) | 2010-03-17 | — | — | EP | claimed |
| EP-1767545-B1 | GLP-1 (Glucagon-like peptide-1) fusion polypeptides with increased peptidase resistance | BIOCOMPATIBLES UK LTD (GB) | 2009-11-11 | — | — | EP | claimed |
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | claimed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | claimed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | claimed |