Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772836 | 0.87 | HTR2A (0.31) | KDM4EKMT2A | |
| SCHEMBL873141 | 0.83 | — | — | |
| SCHEMBL7405510 | 0.82 | KDM4E (0.41) | KDM4EKMT2ADPP9DPP7OPRM1 | |
| Hydrochloric Acid SCHEMBL11029381 | 0.80 | — | — | |
| SCHEMBL2827340 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL2833245 | 0.78 | — | — | |
| SCHEMBL2831752 | 0.76 | TSHR (0.36) | TSHR | |
| SCHEMBL2832088 | 0.76 | TSHR (0.36) | TSHR | |
| SCHEMBL1840485 | 0.76 | TSHR (0.36) | TSHR | |
| SCHEMBL27586398 | 0.75 | KDM4E (0.36) | KDM4EKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518080-B1 | Antibiotic peptides | AMP THERAPEUTICS GMBH (DE) | 2016-05-18 | — | — | EP | claimed |
| EP-2170928-B1 | ANTIBIOTIC PEPTIDES | AMP THERAPEUTICS GMBH (DE) | 2013-07-03 | — | — | EP | claimed |
| EP-0958305-B1 | INHIBITIONS OF THE INTERACTION BETWEEN P53 AND MDM2 | CANCER REC TECH LTD (GB) | 2008-06-04 | — | — | EP | claimed |