Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093665 | 0.98 | TSHR (0.77) | TSHRALDH1A1TP53FAAHCES2 | |
| SCHEMBL7728588 | 0.93 | TSHR (0.71) | TSHRALDH1A1TP53FAAHCES2 | |
| SCHEMBL28140134 | 0.93 | ALDH1A1 (0.76) | TSHRALDH1A1TP53FAAHCES2 | |
| SCHEMBL28252945 | 0.93 | TSHR (0.70) | TSHRALDH1A1TP53FAAHCES2 | |
| Methylene Chloride SCHEMBL28087333 | 0.91 | TSHR (0.90) | TSHRALDH1A1TP53CES2CES1 | |
| Methylene Chloride SCHEMBL28793823 | 0.91 | TSHR (0.90) | TSHRALDH1A1TP53CES2CES1 | |
| Methylene Chloride SCHEMBL28998133 | 0.91 | TSHR (0.90) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL825395 | 0.91 | — | — | |
| SCHEMBL1339298 | 0.91 | TSHR (1.00) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL1339420 | 0.91 | TSHR (1.00) | TSHRALDH1A1TP53CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431139-B | For carrying out the stereospecificity lipid of local treatment with the stimulation-sensibility nano-carrier system recycled for a long time | 特默佐梅有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-105431139-A | Stereospecific lipids for locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems | THERMOSOME GmbH | 2016-03-23 | — | — | CN | disclosed |