Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620753 | 1.00 | LMNA (0.46) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL9234224 | 0.95 | LMNA (0.52) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL19480603 | 0.82 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL29620322 | 0.80 | LMNA (0.50) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL21014430 | 0.80 | LMNA (0.50) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL29803938 | 0.78 | TDP1 (0.43) | TDP1 | |
| SCHEMBL16620465 | 0.78 | TDP1 (0.43) | TDP1 | |
| SCHEMBL28331576 | 0.78 | TDP1 (0.43) | TDP1 | |
| SCHEMBL29009257 | 0.78 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL28582582 | 0.77 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792852-B | Glucose-responsive insulin conjugates | 默沙东公司 | 2019-12-10 | — | — | CN | disclosed |