SCHEMBL28333343

SCHEMBL28333343

CCOC(=O)c1cc(-c2ccccc2)c2cc(Cl)ccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP1A2 P05177 4/20 0.52
HPGD P15428 3/20 0.52
CYP2C19 P33261 3/20 0.52
XBP1 P17861 1/20 0.52
CSF1R P07333 1/20 0.49
ALOX5 P09917 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
ALOX15 P16050 2/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CYP2C9 P11712 2/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 1/20 0.44
CCR6 P51684 1/20 0.44
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27933355 0.88 CCR6 (0.53) ALDH1A1HPGDSMN1; SMN2ALOX15GAA
SCHEMBL28335553 0.88 MAPK1 (0.56) ALDH1A1HPGDSMN1; SMN2ALOX15GAA
SCHEMBL28335604 0.85 ALDH1A1 (0.50) ALDH1A1HPGDALOX5SMN1; SMN2ALOX15
SCHEMBL28333208 0.85 ALDH1A1 (0.47) ALDH1A1CYP1A2HPGDCYP2C19SMN1; SMN2
SCHEMBL28068265 0.85 ALDH1A1 (0.50) ALDH1A1CYP1A2HPGDCYP2C19SMN1; SMN2
SCHEMBL28333205 0.84 ALDH1A1 (0.53) ALDH1A1CYP1A2HPGDCYP2C19SMN1; SMN2
SCHEMBL28333209 0.84 KDM4E (0.57) ALDH1A1CYP1A2HPGDCYP2C19SMN1; SMN2
SCHEMBL28333210 0.82 HSD17B10 (0.44) ALDH1A1CYP1A2HPGDALOX5SMN1; SMN2
SCHEMBL4276707 0.82 TSHR (0.54) ALDH1A1CYP1A2HPGDCYP2C19XBP1
SCHEMBL28335530 0.81 ERN1 (0.51) ALDH1A1CYP1A2HPGDCYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110552018-B Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization 广西师范大学 2021-03-05 CN disclosed
CN-110552018-A Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization UNIV GUANGXI NORMAL 2019-12-10 CN disclosed