SCHEMBL28333378

SCHEMBL28333378

[SiH3]c1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
HNF4A P41235 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
BACE1 P56817 1/20 0.39
LIMK1 P53667 2/20 0.38
CLK4 Q9HAZ1 2/20 0.38
MAP4K4 O95819 1/20 0.38
CSF1R P07333 1/20 0.38
FGFR1 P11362 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL192418 0.84 ALDH1A1 (0.50) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL1557139 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
Charcoal, Activated SCHEMBL30690883 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
Ammonia Solution, Strong SCHEMBL21647364 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL29093087 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL2806539 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL9469764 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
Water SCHEMBL432858 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
Phosphine SCHEMBL10935474 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL28995730 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111095589-B Organic electroluminescent element 株式会社日本触媒 2022-08-09 CN disclosed
CN-114375506-A Organic thin film, method for producing organic thin film, organic electroluminescent element, display device, lighting device, organic thin film solar cell, photoelectric conversion element, thin film transistor, coating composition, and material for organic electroluminescent element 日本放送协会 2022-04-19 CN disclosed
CN-114341144-A Organic thin film, method for producing organic thin film, organic electroluminescent element, display device, lighting device, organic thin film solar cell, thin film transistor, photoelectric conversion element, coating composition, and material for organic electroluminescent element 日本放送协会 2022-04-12 CN disclosed
CN-107710443-B Organic thin film, method for producing organic thin film, organic electroluminescent element, display device, lighting device, organic thin film solar cell, thin film transistor, and coating composition 日本放送协会 2019-12-17 CN disclosed
CN-110540548-A Material for organic electroluminescent element and organic electroluminescent element NIPPON CATALYTIC CHEM IND 2019-12-06 CN disclosed