Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655383 | 0.99 | KDM4E (0.41) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| SCHEMBL28656756 | 0.87 | CYP19A1 (0.39) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| SCHEMBL28333975 | 0.86 | CYP19A1 (0.38) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| Phosphoric Acid SCHEMBL28333981 | 0.82 | PPARA (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28334390 | 0.80 | TUBB1 (0.40) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| SCHEMBL13991618 | 0.79 | TUBB4A (0.61) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| SCHEMBL28333972 | 0.78 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Phosphoric Acid SCHEMBL28333978 | 0.77 | CYP19A1 (0.36) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28654468 | 0.75 | TUBB1 (0.48) | KDM4EALDH1A1PKMTUBB1TUBB4A | |
| SCHEMBL28659072 | 0.74 | TUBB1 (0.47) | KDM4EALDH1A1PKMTUBB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526805-B | Fluorine substituted diphenylethane derivative, preparation method and application | 上海应用技术大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-110526805-A | A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application | SHANGHAI INST TECH | 2019-12-03 | — | — | CN | disclosed |