Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 6/20 | 0.91 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.91 |
| ▸ | MAOB | P27338 | 1/20 | 0.76 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.74 |
| ▸ | TTR | P02766 | 4/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethyl Cinnamate SCHEMBL4351248 | 0.95 | AKR1B10 (1.00) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| Phenethyl Cinnamate SCHEMBL43631 | 0.95 | AKR1B10 (1.00) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| Phenethyl Cinnamate SCHEMBL43632 | 0.95 | AKR1B10 (1.00) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| Phenethyl Cinnamate SCHEMBL28202159 | 0.87 | AKR1B10 (0.83) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL9277968 | 0.87 | AKR1B10 (0.83) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL16234738 | 0.87 | AKR1B10 (0.83) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL19279512 | 0.87 | AKR1B10 (0.83) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL7377864 | 0.87 | AKR1B10 (1.00) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL7377862 | 0.87 | AKR1B10 (1.00) | AKR1B10AKR1B1MAOBHCAR2TTR | |
| SCHEMBL1532424 | 0.86 | AKR1B10 (0.84) | AKR1B10AKR1B1MAOBHCAR2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494539-A | Bicyclic [2.2.1] hept-2-ene\" base-acetic acid esters of 5- is as aromatic and/or flavoring agent | SYMRISE AG | 2019-11-22 | — | — | CN | disclosed |