Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334137 | 1.00 | NR1H2 (0.56) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL698422 | 0.92 | NR1H2 (0.54) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL698218 | 0.92 | NR1H2 (0.54) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL27854990 | 0.92 | NR1H2 (0.54) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL8923537 | 0.89 | NR1H2 (0.52) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL7860307 | 0.89 | NR1H2 (0.52) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL7860304 | 0.89 | NR1H2 (0.52) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL2083157 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL873789 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3DPP4STSHDAC1 | |
| SCHEMBL873617 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3DPP4STSHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001259-B | Substituted azetidine derivatives as TAAR ligands | 豪夫迈·罗氏有限公司 | 2019-12-06 | — | — | CN | disclosed |