Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.54 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698422 | 1.00 | NR1H2 (0.54) | NR1H2NR1H3DAGLAKLK7ABHD6 | |
| SCHEMBL698218 | 1.00 | NR1H2 (0.54) | NR1H2NR1H3DAGLAKLK7ABHD6 | |
| SCHEMBL28334140 | 0.92 | NR1H2 (0.56) | NR1H2NR1H3DAGLAKLK7DPP4 | |
| SCHEMBL28334137 | 0.92 | NR1H2 (0.56) | NR1H2NR1H3DAGLAKLK7DPP4 | |
| SCHEMBL8924617 | 0.90 | DAGLA (0.51) | NR1H2NR1H3DAGLAABHD6HSD11B1 | |
| SCHEMBL10132334 | 0.88 | NPSR1 (0.50) | NR1H2NR1H3OPRD1DPP4MEN1 | |
| SCHEMBL23478097 | 0.87 | CCR3 (0.47) | NR1H2NR1H3DAGLAABHD6 | |
| SCHEMBL10132250 | 0.87 | CCR3 (0.47) | NR1H2NR1H3DAGLAABHD6 | |
| SCHEMBL10132293 | 0.87 | ALDH1A1 (0.51) | NR1H2NR1H3OPRD1MEN1KMT2A | |
| SCHEMBL1992473 | 0.87 | FPR3 (0.52) | NR1H2NR1H3OPRD1KDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102427731-A | Hepatitis c virus inhibitors | ENANTA PHARM INC | 2012-04-25 | — | — | CN | disclosed |