Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334408 | 1.00 | ALDH1A1 (0.40) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL18609579 | 0.88 | MEN1 (0.45) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL18608053 | 0.88 | MEN1 (0.45) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL28332156 | 0.84 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2NPSR1NPC1MAPT | |
| SCHEMBL28332157 | 0.84 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2NPSR1NPC1MAPT | |
| SCHEMBL10132293 | 0.81 | ALDH1A1 (0.51) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL22036268 | 0.80 | HPGD (0.49) | ALDH1A1STSNR1H2NR1H3MEN1 | |
| SCHEMBL18589350 | 0.78 | ALDH1A1 (0.41) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL20628853 | 0.78 | ALDH1A1 (0.41) | ALDH1A1STSHTTSMN1; SMN2NPSR1 | |
| SCHEMBL18607980 | 0.78 | ALDH1A1 (0.41) | ALDH1A1STSHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001259-B | Substituted azetidine derivatives as TAAR ligands | 豪夫迈·罗氏有限公司 | 2019-12-06 | — | — | CN | disclosed |