Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 10/20 | 0.53 |
| ▸ | RPS6KA4 | O75676 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469348 | 0.81 | POLB (0.46) | RPS6KA5NOTUMROCK1HSD11B1CYP1A2 | |
| SCHEMBL28337485 | 0.79 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4CYP1A2CYP2A6LMNA | |
| SCHEMBL29961184 | 0.79 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4ROCK1CYP1A2LMNA | |
| SCHEMBL28335134 | 0.79 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4ROCK1KDM4EMAPT | |
| SCHEMBL28901199 | 0.79 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4ROCK1HSP90AA1MAPT | |
| SCHEMBL29022359 | 0.76 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4CYP1A2CYP2A6KDM4E | |
| SCHEMBL26685153 | 0.75 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4KDM4ELMNA | |
| SCHEMBL28337545 | 0.75 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4ROCK1MAPT | |
| SCHEMBL3141727 | 0.74 | NOTUM (0.46) | NOTUMROCK1HSD11B1CYP1A2CYP2A6 | |
| SCHEMBL3302135 | 0.72 | POLB (0.50) | RPS6KA5METCYP1A2KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563701-B | N-2-pyrimidine-2-azido-3- (2,2,6, 6-tetramethylpiperidinyloxy) indoline and preparation and application thereof | 浙江工业大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-110563701-A | N-2-pyrimidine-2-azido-3- (2,2,6, 6-tetramethylpiperidinyloxy) indoline and preparation and application thereof | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |