Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335263 | 0.81 | RPS6KA5 (0.53) | ROCK1NOTUMRPS6KA5KDM4EHSD11B1 | |
| SCHEMBL28459603 | 0.81 | POLB (0.46) | POLBPTK2ROCK1RPS6KA5HSD17B10 | |
| SCHEMBL28460368 | 0.81 | POLB (0.46) | POLBPTK2ROCK1RPS6KA5HSD17B10 | |
| SCHEMBL28679956 | 0.81 | POLB (0.46) | POLBPTK2ROCK1RPS6KA5HSD17B10 | |
| SCHEMBL8539865 | 0.80 | POLB (0.49) | POLBPTK2HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL30297960 | 0.79 | GAA (0.47) | POLBPTK2RPS6KA5HSD17B10KDM4E | |
| SCHEMBL9385489 | 0.79 | GAA (0.47) | POLBPTK2RPS6KA5HSD17B10KDM4E | |
| SCHEMBL15999061 | 0.76 | ROCK1 (0.48) | POLBROCK1KDM4E | |
| SCHEMBL3141727 | 0.74 | NOTUM (0.46) | POLBROCK1NOTUMKDM4ESMN1; SMN2 | |
| SCHEMBL31107087 | 0.74 | CDC7 (0.60) | POLBPTK2ROCK1RPS6KA5HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511208-B | N-2-pyridyl-2, 3-diazido indoline compound and preparation and application thereof | 浙江工业大学 | 2020-08-25 | — | — | CN | disclosed |