Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354390 | 0.81 | HSD17B10 (0.41) | MGLLPTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL3790254 | 0.80 | MGLL (0.53) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL16426680 | 0.80 | MGLL (0.57) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL22002013 | 0.80 | MGLL (0.57) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL29993805 | 0.79 | HPGD (0.43) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL20254041 | 0.78 | MGLL (0.61) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL29239350 | 0.77 | PTGS1 (0.39) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL8391712 | 0.77 | MGLL (0.53) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL28344379 | 0.76 | MGLL (0.44) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| SCHEMBL4619178 | 0.74 | MGLL (0.43) | MGLLPTGS1PTGS2FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801107-A | Benzazepine derivatives, conjugates containing same and application thereof | 上海迪诺医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-109912683-B | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-115505029-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-112826940-A | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-105641707-B | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-110621673-A | Double-stranded linked cytotoxic drug conjugates | 杭州多禧生物科技有限公司 | 2019-12-27 | — | — | CN | disclosed |