Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 11/20 | 0.60 |
| ▸ | CHUK | O15111 | 10/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987784 | 0.84 | KEAP1 (0.56) | IKBKBCHUKPDPK1KEAP1DHODH | |
| SCHEMBL29898213 | 0.81 | IKBKB (0.62) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL20884986 | 0.80 | IKBKB (0.57) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL988102 | 0.80 | NR4A2 (0.44) | IKBKBCHUKPDPK1KEAP1 | |
| SCHEMBL552112 | 0.79 | IKBKB (0.60) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL20884066 | 0.79 | IKBKB (0.56) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL4686346 | 0.77 | IKBKB (0.74) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL3802579 | 0.76 | IKBKB (1.00) | IKBKBCHUKPDPK1 | |
| SCHEMBL4687001 | 0.75 | IKBKB (0.63) | IKBKBCHUKPDPK1ADRB1KEAP1 | |
| SCHEMBL4686999 | 0.75 | IKBKB (0.63) | IKBKBCHUKPDPK1ADRB1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-A | It can be used as the indole carboxamides compound of kinase inhibitor | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |