SCHEMBL28336007

SCHEMBL28336007

COC(=O)/C(=C/c1cn(C2CCC(C)CC2)cn1)CCCNC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 11/20 0.36
STK17B O94768 1/20 0.35
STK17A Q9UEE5 1/20 0.35
SIGMAR1 Q99720 1/20 0.33
DRD2 P14416 3/20 0.33
GFER P55789 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
FPR3 P25089 1/20 0.33
FPR2 P25090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14653711 1.00 CPB2 (0.36) CPB2STK17BSTK17ASIGMAR1DRD2
SCHEMBL19159434 1.00 CPB2 (0.36) CPB2STK17BSTK17ASIGMAR1DRD2
SCHEMBL17750090 0.92 CPB2 (0.37) CPB2STK17BSTK17ASIGMAR1DRD2
SCHEMBL14630708 0.92 CPB2 (0.39) CPB2STK17BSTK17ASIGMAR1GFER
SCHEMBL14630714 0.92 CPB2 (0.39) CPB2STK17BSTK17ASIGMAR1GFER
SCHEMBL17615820 0.92 CPB2 (0.41) CPB2STK17BSTK17ASIGMAR1DRD2
SCHEMBL20893299 0.92 CPB2 (0.39) CPB2STK17BSTK17ASIGMAR1GFER
SCHEMBL14630711 0.92 CPB2 (0.39) CPB2STK17BSTK17ASIGMAR1GFER
SCHEMBL19447714 0.92 CPB2 (0.39) CPB2STK17BSTK17ASIGMAR1GFER
SCHEMBL14650464 0.85 CPB2 (0.37) CPB2STK17BSTK17ASIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801489-B Cycloalkyl-substituted imidazole derivatives 第一三共株式会社 2019-12-10 CN disclosed