Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28337022

NC(=O)C1CNC1.O=C(O)C(F)(F)F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
NOS2 P35228 1/20 0.39
SLC6A2 P23975 4/20 0.35
SLC6A4 P31645 4/20 0.35
SLC6A3 Q01959 4/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
SLC6A1 P30531 2/20 0.33
SLC6A11 P48066 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC6A13 Q9NSD5 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29678829 1.00 CYP2D6 (0.45) CYP2D6KDM4EMAPTKMT2AATM
Trifluoroacetic Acid SCHEMBL23779156 0.84 KDM4E (0.58) CYP2D6KDM4EMAPTKMT2AATM
Trifluoroacetic Acid SCHEMBL3450626 0.84 KDM4E (0.58) CYP2D6KDM4EMAPTKMT2AATM
Trifluoroacetic Acid SCHEMBL30478376 0.84 KDM4E (0.58) CYP2D6KDM4EMAPTKMT2AATM
SCHEMBL1366389 0.83
Trifluoroacetic Acid SCHEMBL30385180 0.82 SLC6A1 (0.45) CYP2D6SLC6A2SLC6A4SLC6A3CYP1A2
Trifluoroacetic Acid SCHEMBL28172134 0.81 KDM4E (0.76) CYP2D6KDM4EMAPTKMT2AATM
Hydrochloric Acid SCHEMBL3228194 0.81
Ammonia Solution, Strong SCHEMBL28141684 0.81
Water SCHEMBL28310277 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520422-B Novel pyridonecarboxylic acid derivative or salt thereof 涌永制药株式会社 2023-09-05 CN disclosed
CN-115427406-A 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same 株式会社钟根堂 2022-12-02 CN disclosed
CN-110520422-A Novel pyridone carboxylic acid derivatives or its salt WAKUNAGA PHARMA CO LTD 2019-11-29 CN disclosed