Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.85 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681571 | 0.98 | TDP1 (0.89) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Hydrochloric Acid SCHEMBL29205003 | 0.96 | TDP1 (0.85) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| SCHEMBL28193002 | 0.96 | TDP1 (0.85) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Fluoride SCHEMBL29204969 | 0.96 | TDP1 (0.85) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| SCHEMBL18301254 | 0.96 | TDP1 (0.85) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Bromide SCHEMBL15822430 | 0.94 | TDP1 (0.96) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Bromide SCHEMBL28575958 | 0.92 | TDP1 (0.93) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Bromide SCHEMBL18141892 | 0.92 | TDP1 (0.93) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Bromide SCHEMBL3191407 | 0.92 | TDP1 (0.93) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 | |
| Dimethylamine SCHEMBL7749424 | 0.92 | TDP1 (0.79) | TDP1L3MBTL1CYP2A6HRH1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-104617338-B | Sodium rechargeable battery comprising forming slotted graphite felt | SK新技术株式会社 | 2019-11-12 | — | — | CN | disclosed |