Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 18/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481374 | 0.84 | ITGAV (0.46) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL30335853 | 0.79 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL26891080 | 0.77 | ITGAV (0.46) | ITGAVITGB3ITGB6 | |
| SCHEMBL4762028 | 0.77 | ITGB3 (0.50) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL20481236 | 0.75 | ITGAV (0.49) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL20481005 | 0.75 | ITGAV (0.44) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL29429453 | 0.74 | ITGAV (0.57) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL21715684 | 0.73 | ITGAV (0.40) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL7095811 | 0.73 | ITGB3 (0.52) | ITGAVITGB3ITGB5ITGB1 | |
| SCHEMBL7098375 | 0.72 | ITGAV (0.50) | ITGAVITGB3ITGB5ITGB1ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573499-A | inhibitors of α v β 6 integrin | 莫菲克医疗股份有限公司 | 2019-12-13 | — | — | CN | disclosed |