Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337206 | 1.00 | GSK3A (0.38) | GSK3AGSK3BALOX15ELANEITGB3 | |
| SCHEMBL20481180 | 0.84 | MEN1 (0.36) | GSK3AGSK3BELANEPOLBALDH1A1 | |
| SCHEMBL20481179 | 0.84 | MEN1 (0.36) | GSK3AGSK3BELANEPOLBALDH1A1 | |
| SCHEMBL407909 | 0.74 | PPARG (0.43) | ALOX15POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22009031 | 0.71 | ABL1 (0.42) | GSK3AGSK3BALOX15ELANEPOLB | |
| SCHEMBL2903470 | 0.71 | POLB (0.40) | POLBTDP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10369695 | 0.70 | GSK3A (0.42) | GSK3AGSK3BALOX15ELANEPOLB | |
| SCHEMBL30604703 | 0.70 | ACE (0.46) | GSK3AGSK3BALOX15ELANEPOLB | |
| SCHEMBL2828076 | 0.68 | GAA (0.49) | GSK3AGSK3BALOX15ELANEPOLB | |
| SCHEMBL20481035 | 0.68 | GSK3B (0.41) | GSK3AGSK3BALOX15ELANEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573499-A | inhibitors of α v β 6 integrin | 莫菲克医疗股份有限公司 | 2019-12-13 | — | — | CN | disclosed |