Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337611 | 1.00 | ALDH1A1 (0.42) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL20529532 | 0.93 | ALDH1A1 (0.45) | ALDH1A1PPARGPPARAATMAAK1 | |
| SCHEMBL20529531 | 0.93 | ALDH1A1 (0.45) | ALDH1A1PPARGPPARAATMAAK1 | |
| SCHEMBL20529533 | 0.93 | ALDH1A1 (0.45) | ALDH1A1PPARGPPARAATMAAK1 | |
| SCHEMBL28509153 | 0.90 | ALDH1A1 (0.42) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL18918272 | 0.87 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL18925550 | 0.87 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL19473311 | 0.87 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL28337627 | 0.87 | ATM (0.42) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL29390410 | 0.87 | ATM (0.42) | ALDH1A1PPARGPPARAATMMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110099682-B | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113195487-A | 2, 3-diaminosuccinyl conjugate linkers | 杭州多禧生物科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-110621673-A | Double-stranded linked cytotoxic drug conjugates | 杭州多禧生物科技有限公司 | 2019-12-27 | — | — | CN | disclosed |