SCHEMBL28337643

SCHEMBL28337643

O[C@H](c1ccc(F)cc1)[C@H]1CO1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
HTR2A P28223 3/20 0.41
HTR2C P28335 1/20 0.41
HTR7 P34969 1/20 0.41
KDM4E B2RXH2 1/20 0.39
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337646 1.00 EPHX1 (0.43) EPHX1HTR2AHTR2CHTR7KDM4E
SCHEMBL1237578 0.80 POLB (0.42) EPHX1HTR2AHTR2CHTR7KDM4E
SCHEMBL29087977 0.79 SLC6A3 (0.39)
SCHEMBL28335313 0.79 SLC6A3 (0.39)
SCHEMBL28335311 0.79 SLC6A3 (0.39)
SCHEMBL2411371 0.78 EPHX1 (0.48) EPHX1
SCHEMBL5001664 0.78 EPHX1 (0.48) EPHX1
SCHEMBL5001663 0.78 EPHX1 (0.48) EPHX1
SCHEMBL4992445 0.78 EPHX1 (0.48) EPHX1
SCHEMBL4992437 0.78 EPHX1 (0.48) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110564755-B Method for preparing (S) -3-phenyl-1, 2-epoxypropane and derivatives thereof by using biological enzyme catalysis 河南农业大学 2021-01-12 CN disclosed
CN-110564755-A Method for preparing (S) -3-phenyl-1, 2-epoxypropane and derivatives thereof by using biological enzyme catalysis 河南农业大学 2019-12-13 CN disclosed