Toluene

Toluene

SCHEMBL28337909

CCCCP.Cc1ccccc1.Cc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.52
ALOX12 P18054 1/20 0.52
ACHE P22303 1/20 0.52
PCSK9 Q8NBP7 1/20 0.42
HTT P42858 1/20 0.39
LTA4H P09960 2/20 0.38
PTGS2 P35354 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CNR2 P34972 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3671880 1.00 TSHR (0.52) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL11618017 1.00 TSHR (0.52) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL80497 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL10941851 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL1549759 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL6257976 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL2990240 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL1155205 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL18640410 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9
Toluene SCHEMBL27422075 0.85 TSHR (0.65) TSHRLMNAALOX12ACHEPCSK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511151-A A kind of compound, the organic electroluminescence device comprising it and its application BEIJING ETERNAL MAT TECH CO LTD 2019-11-29 CN disclosed