SCHEMBL28338264

SCHEMBL28338264

C=Cc1ccc(C(C)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
TSHR P16473 2/20 0.54
ESR1 P03372 3/20 0.54
ESR2 Q92731 3/20 0.54
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.38
HDAC8 Q9BY41 1/20 0.37
CYP19A1 P11511 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2B6 P20813 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
TP53 P04637 1/20 0.34
KCNN4 O15554 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ESRRG P62508 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13955702 0.91 ESR1 (0.71) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL3337526 0.87 ALDH1A1 (0.54) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL30335827 0.85 CYP19A1 (0.45) ALDH1A1TSHRESR1ESR2MAPK1
SCHEMBL28980117 0.85 CYP19A1 (0.45) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL29066407 0.83 ALDH1A1 (0.50) ALDH1A1TSHRESR1ESR2CYP3A4
Styrene SCHEMBL7512832 0.83 ALDH1A1 (0.61) ALDH1A1TSHRMAPK1HDAC8TDP1
SCHEMBL9650220 0.81 PPARG (0.49)
SCHEMBL5887915 0.81 ESR1 (0.75) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL16626142 0.78 ALDH1A1 (0.54) ALDH1A1TSHRHDAC8TDP1KCNN4
SCHEMBL5200003 0.78 ALDH1A1 (0.54) ALDH1A1TSHRESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110591184-B Styrene polymer antibacterial material and preparation method thereof 泉州师范学院 2022-03-11 CN claimed
CN-110591184-A Styrene polymer antibacterial material and preparation method thereof 泉州师范学院 2019-12-20 CN claimed
CN-110591184-B Styrene polymer antibacterial material and preparation method thereof 泉州师范学院 2022-03-11 CN disclosed
CN-110591184-A Styrene polymer antibacterial material and preparation method thereof 泉州师范学院 2019-12-20 CN disclosed