Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850879 | 0.88 | LMNA (0.42) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL780017 | 0.82 | TDP1 (0.52) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL29468594 | 0.82 | TDP1 (0.52) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL779846 | 0.82 | LMNA (0.42) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL25256710 | 0.82 | SRC (0.58) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL29427945 | 0.82 | SRC (0.58) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL28336686 | 0.82 | NPC1 (0.46) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL12230088 | 0.79 | CA12 (0.41) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL28074474 | 0.79 | NPC1 (0.47) | NPC1RAB9AKDM4ECASP3SENP7 | |
| SCHEMBL27637358 | 0.76 | NPC1 (0.42) | NPC1RAB9AKDM4ECASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437280-A | A kind of new method preparing 2 '-iodos [1,1 '-biaryl] -2- organic phosphonate compounds | HUNAN INST SCIENCE & TECH | 2019-11-12 | — | — | CN | disclosed |