Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.63 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405704 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL29500136 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL141605 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL3400752 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL29234687 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL29468039 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL32679826 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL31124557 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL31588397 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL30963953 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996486-A | Local delivery of therapeutic agents comprising cell penetrating peptides for the treatment of age-related macular degeneration and other eye diseases | K·罗伊兹曼 | 2021-06-18 | — | — | CN | disclosed |
| CN-110545836-A | Treatment of age-related macular degeneration and other ocular diseases with apolipoprotein mimics | MACREGEN INC | 2019-12-06 | — | — | CN | disclosed |