Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.63 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405704 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| Biphenyl SCHEMBL28338714 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL141605 | 1.00 | CYP2A6 (0.83) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL3400752 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL29234687 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL29468039 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL32679826 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL31124557 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL31588397 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL30963953 | 0.97 | CYP2A6 (0.79) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717459-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PEPTIDREAM INC (JP) | 2026-01-15 | — | — | US | disclosed |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | NIPPON SHINYAKU CO., LTD. (JP) | 2025-12-30 | — | — | US | disclosed |
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| US-12065446-B2 | Inhibitors of Bruton's tyrosine kinase and method of their use | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-20 | — | — | US | disclosed |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-06-06 | — | — | US | disclosed |
| CN-117820253-A | 3, 6-disubstituted benzothiazole compound and synthesis and application thereof | 西北农林科技大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-112375067-B | Substituted 2-anilinopyrimidine derivatives and their use as epidermal growth factor receptor modulators | 贝达医药公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-112687815-B | Organic light emitting diode and organic light emitting device including the same | 乐金显示有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
| CN-116947843-A | 3, 5-disubstituted benzothia (oxa) azole compounds, synthesis and application thereof | 西北农林科技大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116848107-A | Compounds and their use as PDE4 activators | 米罗尼德有限公司 | 2023-10-03 | — | — | CN | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230097422-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | US | disclosed |
| US-20230101484-A1 | COMPOUND AND COMPOSITION AS PDGF RECEPTOR KINASE INHIBITOR | NIPPON SHINYAKU CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20230086703-A1 | N-(4-(5-chloropyridin-3-yl)phenyl)-2-(2-(cyclopropanesulfonamido)pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | STEP PHARMA S.A.S. (FR) | 2023-03-23 | — | — | US | disclosed |
| US-11319329-B2 | Inhibitors of Bruton's tyrosine kinase and methods of their use | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065446-B2 | Inhibitors of Bruton's tyrosine kinase and method of their use | ABL1, BTK, LYN | CYP2A6 3762/4885ALDH1A1 4036/4885CYP3A4 3311/4885 |
| US-20230086703-A1 | N-(4-(5-chloropyridin-3-yl)phenyl)-2-(2-(cyclopropanesulfonamido)pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | CTPS1, CTPS2, CERS2 | CYP2A6 1643/4885ALDH1A1 2214/4885CYP3A4 2600/4885 |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | NSUN3, BCAT1, SLC43A1 | CYP2A6 1570/4885ALDH1A1 2330/4885CYP3A4 1322/4885 |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | PDGFRA, PDGFRB, PDGFA | CYP2A6 3817/4885ALDH1A1 1938/4885CYP3A4 4446/4885 |
| US-20230097422-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE | ABL1, BTK, LYN | CYP2A6 3762/4885ALDH1A1 4036/4885CYP3A4 3311/4885 |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | PTPN2, PTPN22, PTPN1 | CYP2A6 2027/4885ALDH1A1 3561/4885CYP3A4 3555/4885 |
| US-20230101484-A1 | COMPOUND AND COMPOSITION AS PDGF RECEPTOR KINASE INHIBITOR | PDGFRB, PDGFRA, PDGFA | CYP2A6 3529/4885ALDH1A1 2989/4885CYP3A4 4501/4885 |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | CYP2A6 4516/4885ALDH1A1 4385/4885CYP3A4 4397/4885 |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | CYP2A6 3665/4885ALDH1A1 3122/4885CYP3A4 3921/4885 |
| US-11319329-B2 | Inhibitors of Bruton's tyrosine kinase and methods of their use | ABL1, BTK, MYLK2 | CYP2A6 4169/4885ALDH1A1 3938/4885CYP3A4 3769/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | CYP2A6 4365/4885ALDH1A1 4472/4885CYP3A4 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.