Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791920 | 0.88 | KMT2A (0.50) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL1592263 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL16672682 | 0.83 | HCAR2 (0.47) | ALDH1A1TDP1MAPK1L3MBTL1CES1 | |
| SCHEMBL19185364 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL18287624 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL14101169 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL28107631 | 0.82 | CA1 (0.47) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL1320975 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL4918220 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL2678884 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62241906-A | — | — | None | — | — | JP | disclosed |
| US-12324802-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250122218-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2025-04-17 | — | — | US | disclosed |
| EP-4476230-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2024-12-18 | — | — | EP | disclosed |
| EP-4247817-A1 | MACROCYCLES CONTAINING A 1,3,4-OXADIAZOLE RING FOR USE AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116670140-A | Macrocyclic compounds containing 1,3, 4-oxadiazole rings as modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023154291-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154291-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20230099745-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2023-03-30 | — | — | US | disclosed |
| US-6586530-B1 | controlled radical (co)polymerization process to produce the low surface tension (meth)acrylate containing block copolymers. | PPG INDUSTRIES OHIO, INC. | 2003-07-01 | — | — | US | disclosed |
| US-6583223-B2 | First block is radically polymerizable fluoroalkyl(meth)acrylate monomer, second block is ethylenically unsaturated monomer that is free of hydroxyl groups and amine groups; thermosetting reactants | PPG INDUSTRIES OHIO, INC. | 2003-06-24 | — | — | US | disclosed |
| US-20030114593-A1 | Low surface tension (meth) acrylate containing block copolymer prepared by controlled radical polymerization | PPG INDUSTRIES OHIO, INC. | 2003-06-19 | — | — | US | disclosed |
| US-20030100675-A1 | Coating compositions which contain a low surface tension (meth) acrylate containing block copolymer flow control agent | PPG INDUSTRIES OHIO, INC. | 2003-05-29 | — | — | US | disclosed |
| US-20030096929-A1 | Copolymers comprising low surface tension (meth) acrylates | PPG INDUSTRIES OHIO, INC. | 2003-05-22 | — | — | US | disclosed |
| WO-2003027159-A2 | COMPOSITIONS CONTAINING A LOW SURFACE TENSION (METH)ACRYLATE CONTAINING BLOCK COPOLYMER | PPG INDUSTRIES OHIO, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003027155-A1 | COPOLYMERS COMPRISING LOW SURFACE TENSION (METH)ACRYLATES | PPG INDUSTRIES OHIO, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| EP-0271212-B1 | PROCESS FOR PREPARATION OF CARBOXYLIC ACID ESTER CONTAINING FLUORINE | Tosoh Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0271212-A2 | Process for preparation of carboxylic acid ester containing fluorine | Tosoh Corporation (JP) | 1988-06-15 | — | — | EP | disclosed |
| JP-S62241906-A | FLUORINE-CONTAINING POLYMER | TOSOH CORP | 1987-10-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122218-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | ALDH1A1 3972/4885KMT2A 4654/4885TDP1 4655/4885 |
| US-12324802-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | CFTR, SCNN1G, SCNN1B | ALDH1A1 3972/4885KMT2A 4654/4885TDP1 4655/4885 |
| US-20230099745-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | ALDH1A1 3972/4885KMT2A 4654/4885TDP1 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.