Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339057 | 0.80 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2ADNM1 | |
| SCHEMBL28339091 | 0.78 | KDM4E (0.70) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL14274010 | 0.78 | KDM4E (0.70) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL13993320 | 0.78 | KDM4E (0.70) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL25159695 | 0.78 | MEN1 (0.66) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL28169242 | 0.78 | MEN1 (0.66) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL2098159 | 0.77 | DNM1 (0.57) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL1022224 | 0.77 | DNM1 (0.57) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL2098163 | 0.77 | DNM1 (0.57) | AOC3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL5964083 | 0.76 | CNR2 (0.51) | AOC3KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021884-B | Method for efficiently synthesizing chiral 1, 2-amino alcohol by catalyzing alpha-aminoketone through Ir/f-amphox | 武汉凯特立斯科技有限公司 | 2019-12-24 | — | — | CN | disclosed |
| CN-107021884-A | Method for efficiently synthesizing chiral 1, 2-amino alcohol by catalyzing alpha-aminoketone through Ir/f-amphox | 武汉凯特立斯科技有限公司 | 2017-08-08 | — | — | CN | disclosed |